With over 10 years’ real-world experience, SMOFlipid is a 4-oil intravenous lipid emulsion you can trust. As times are changing, we’re working with clinicians and patients to help provide the support they need. We’re part of a wider package of care, aiming to improve the lives of adults, children and infants.
Look what can be achieved… with a little bit of TLC (Trusted Lipid Care)
SMOFlipid – a 4-oil mix that provides energy and essential fatty acids, with a profile designed to support recovery.1
No other lipid emulsion brand has the same 4-oil mix and fatty acid profile as SMOFlipid.1–5
SMOFlipid is indicated as a supply of energy and essential fatty acids and omega-3(ω-3) fatty acids to patients, as part of a parenteral nutrition regimen, when oral or enteral nutrition is impossible, insufficient or contraindicated.1
SMOFlipid: a trusted 4-oil intravenous lipid emulsion with over 10 years’ real-world experience…1
ω-3 fatty acids have proven benefits for adult hospitalised patients6,7*
Compared with standard PN†, hospitalised adults who received ω-3 fatty-acid enriched PN had a:
- 40% lower risk of infection
(131 vs 215 events; RR 0.60, 95% CI 0.49–0.72; p<0.00001)
- Co-primary endpoint - Shorter ICU stay
(Mean stay length reduced by 1.95 days, 95% CI 0.42–3.49; p=0.01) - 30-day mortality rate
(83 vs 101 events; RR 0.84, 95% CI 0.65–1.07; p=NS)
- Co-primary endpoint - Shorter hospital stay
(Mean stay length reduced by 2.14 days, 95% CI 1.36–2.93; p<0.00001) - 56% lower risk of sepsis(24 vs 54 events; RR 0.44, 95% CI 0.28–0.70; p=0.0004)
- *Systematic Systemic review and meta-analysis of 49 randomised, controlled trials (3641 ICU or surgical patients. For the outcomes of: infection rate, 24 studies, n=2154, ARR = 8%; 30-day mortality, 20 studies, n=1839, ARR = 2%; sepsis, 9 studies, n=1141, ARR = 6%; LOHS, 26 studies, n-2182; ICU stay, 10 studies, n=822).7
†non-ω-3 fatty acid enriched.
ARR, Absolute Risk Reduction; CI, Confidence Interval; ICU, Intensive Care Unit; LOHS, length of hospital stay; NS, Not Significant; PN, Parenteral Nutrition; RR, Relative Risk.
Omega-3 fatty acids can exert beneficial effects on the immune response8
A hypothetical model showing the postulated effects fish oil based omega-3 lipids on immune function.8 Fish oil based omega-3 lipids may lead to a more balanced immune response avoiding a hyper-inflammation and subsequent immune-paralysis. This may lead, perhaps through generation of resolvins, to a faster resolution of inflammation and recovery.8
CARS, Compensatory Anti-Inflammatory Response Syndrome; DHA, Docosahexaenoic Acid; EPA, Eicosapentaenoic Acid; FA, Fatty Acid; IL, Interleukin; SIRS, Systemic Inflammatory Response Syndrome; TGF, Transforming Growth Factor; TNF, Tumour Necrosis Factor
Improved clinical outcomes can translate to cost savings
in healthcare settings10
For each adult patient requiring parenteral nutrition (PN) in the UK, ω-3 fatty acid containing PN could save £2528 ± £942 compared with non-ω-3 fatty acid containing PN.10
For 50 patients per year this could be a saving of £126,400
Equivalent to
4 newly qualified band 5 dieticians*11
Figures derived from a pharmacoeconomic model in adult ICU and surgical patients considering reference costs of treatment and hospital stay based on efficacy outcomes of a meta-analysis.7,10
For a bespoke budget impact estimate of switching from non-ω-3 fatty acid containing PN to ω-3 fatty acid containing PN, contact
parenteral-nutrition.msl@fresenius-kabi.com
*Based on NHS agenda for change pay scale 2021/2022 band 5 (0-2 years’ experience) annual salary of £25,654. https://www.nhsemployers.org/articles/annual-pay-scales-202122
ICU, Intensive Care Unit; PN, Parenteral Nutrition
Ordering SMOFlipid
Item code | 2451031 | 2451061 | 2451091 |
---|---|---|---|
Item description | SMOFlipid® 20% | SMOFlipid® 20% | SMOFlipid® 20% |
Unit size | 100ml | 250ml | 500ml |
Case quantity | 10 | 10 | 10 |
Ordering SMOFlipid
Item code | Item description | Unit size | Case quantity |
---|---|---|---|
2451031 | SMOFlipid® 20% | 100ml | 10 |
2451061 | SMOFlipid® 20% | 250ml | 10 |
2451091 | SMOFlipid® 20% | 500ml | 10 |
How to order:
Our customer service team are available Monday to Friday from 08:30–17:15 to take your order or respond to your queries on 01928 533 697.
They are happy to call you at a pre-arranged time and date to take your order.
Alternatively, you can place an order via: