With over 10 years’ real-world experience, SMOFlipid is a 4-oil intravenous lipid emulsion you can trust. As times are changing, we’re working with clinicians and patients to help provide the support they need. We’re part of a wider package of care, aiming to improve the lives of adults, children and infants.

Look what can be achieved… with a little bit of TLC (Trusted Lipid Care)

Graph showing content percentagesDHA, Docosahexaenoic Acid; EPA, Eicosapentaenoic Acid

SMOFlipid – a 4-oil mix that provides energy and essential fatty acids, with a profile designed to support recovery.1

No other lipid emulsion brand has the same 4-oil mix and fatty acid profile as SMOFlipid.1–5

SMOFlipid is indicated as a supply of energy and essential fatty acids and omega-3(ω-3) fatty acids to patients, as part of a parenteral nutrition regimen, when oral or enteral nutrition is impossible, insufficient or contraindicated.1

SMOFlipid: a trusted 4-oil intravenous lipid emulsion with over 10 years’ real-world experience…1

ω-3 fatty acids have proven benefits for adult hospitalised patients6,7*

Compared with standard PN†, hospitalised adults who received ω-3 fatty-acid enriched PN had a:

  • 40% lower risk of infection
    (131 vs 215 events; RR 0.60, 95% CI 0.49–0.72; p<0.00001)
    - Co-primary endpoint
  • Shorter ICU stay
    (Mean stay length reduced by 1.95 days, 95% CI 0.42–3.49; p=0.01)
  • 30-day mortality rate
    (83 vs 101 events; RR 0.84, 95% CI 0.65–1.07; p=NS)
    - Co-primary endpoint
  • Shorter hospital stay
    (Mean stay length reduced by 2.14 days, 95% CI 1.36–2.93; p<0.00001)
  • 56% lower risk of sepsis(24 vs 54 events; RR 0.44, 95% CI 0.28–0.70; p=0.0004)
  • *Systematic Systemic review and meta-analysis of 49 randomised, controlled trials (3641 ICU or surgical patients. For the outcomes of: infection rate, 24 studies, n=2154, ARR = 8%; 30-day mortality, 20 studies, n=1839, ARR = 2%; sepsis, 9 studies, n=1141, ARR = 6%; LOHS, 26 studies, n-2182; ICU stay, 10 studies, n=822).7
    †non-ω-3 fatty acid enriched.
    ARR, Absolute Risk Reduction; CI, Confidence Interval; ICU, Intensive Care Unit; LOHS, length of hospital stay; NS, Not Significant; PN, Parenteral Nutrition; RR, Relative Risk.

Omega-3 fatty acids can exert beneficial effects on the immune response8

A hypothetical model showing the postulated effects fish oil based omega-3 lipids on immune function.8 Fish oil based omega-3 lipids may lead to a more balanced immune response avoiding a hyper-inflammation and subsequent immune-paralysis. This may lead, perhaps through generation of resolvins, to a faster resolution of inflammation and recovery.8

Inflammation grade by postulated time graphInflammation grade by postulated time graphkey for graphkey for graph

CARS, Compensatory Anti-Inflammatory Response Syndrome; DHA, Docosahexaenoic Acid; EPA, Eicosapentaenoic Acid; FA, Fatty Acid; IL, Interleukin; SIRS, Systemic Inflammatory Response Syndrome; TGF, Transforming Growth Factor; TNF, Tumour Necrosis Factor

Improved clinical outcomes can translate to cost savings
in healthcare settings10

For each adult patient requiring parenteral nutrition (PN) in the UK, ω-3 fatty acid containing PN could save £2528 ± £942 compared with non-ω-3 fatty acid containing PN.10

Yellow patient in bed icon

For 50 patients per year this could be a saving of £126,400

Yellow doctor icon

Equivalent to
4 newly qualified band 5 dieticians*11

Figures derived from a pharmacoeconomic model in adult ICU and surgical patients considering reference costs of treatment and hospital stay based on efficacy outcomes of a meta-analysis.7,10

For a bespoke budget impact estimate of switching from non-ω-3 fatty acid containing PN to ω-3 fatty acid containing PN, contact

*Based on NHS agenda for change pay scale 2021/2022 band 5 (0-2 years’ experience) annual salary of £25,654. https://www.nhsemployers.org/articles/annual-pay-scales-202122

ICU, Intensive Care Unit; PN, Parenteral Nutrition

Bottle of SMOFlipid

Ordering SMOFlipid

SMOFlipid® 20%SMOFlipid® 20%SMOFlipid® 20%

Ordering SMOFlipid

Bottle of SMOFlipid
Item codeItem descriptionUnit sizeCase quantity
2451031SMOFlipid® 20%100ml10
2451061SMOFlipid® 20%250ml10
2451091SMOFlipid® 20%500ml10

How to order:

Our customer service team are available Monday to Friday from 08:30–17:15 to take your order or respond to your queries on 01928 533 697.

They are happy to call you at a pre-arranged time and date to take your order.

Alternatively, you can place an order via:

Telephone:01928 533 697

Fax:01928 533 420



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