SmofKabiven® Low Osmo Peripheral

Compared with other commercially available MCBs licensed for peripheral administration, SmofKabiven Low Osmo Peripheral, based on the kcal content per ml of fluid, and maximum hourly infusion rates and recommended infusion periods for adults, can deliver the most kcal per kg bw/hour.1* It contains SMOFlipid® (soya-bean oil, medium-chain triglycerides, olive oil and fish oil),2 which may have positive effects on patient outcomes.3–6

SmofKabiven Low Osmo Peripheral has the lowest osmolarity, compared with other commercially available MCBs licensed for peripheral administration,1,7–10 within expert guideline recommendations for osmolarities for peripheral PN.11,12*

For total PN, vitamins and trace elements should be administered to the patient in addition to the macronutrients delivered via multi-chamber bags.

Protein – Energy ratio: 1 gAA/29 kcal
Nitrogen – Non-protein kcal ratio: 1:156

Figures are approximations calculated from the summaries of products characteristics.

Contains SMOFlipid

SmofKabiven Low Osmo Peripheral1

Contains SMOFlipid, a four lipid emulsion2

SmofKabiven Low Osmo Peripheral contains the same SMOFlipid found in all the SmofKabiven ranges

  • Shown to have less impact on liver cell function and inflammatory response versus older lipid emulsions3,5,13–15

Contains Aminoven® 16 (amino acids 10%)
SmofKabiven Low Osmo Peripheral provides essential, non-essential and conditionally essential amino acids

  • Contains taurine which may have a hepatoprotective effect17

Efficient energy delivery
SmofKabiven Low Osmo Peripheral provides the most kcal/kg/hour compared with other commercially available MCBs licensed for peripheral use when maximum infusion rates and recommended infusion periods for adults are applied.1,7-10

  • Lowest osmolarity compared with other commercially available MCBs licensed for peripheral administration*1,7-10

For short-term PN
SmofKabiven Low Osmo Peripheral1 is designed to meet the needs of patients requiring short-term nutrition support and for whom energy needs are prioritised

  • Peripheral venous access can be quicker to establish than central venous access, offering the possibility for prompt administration of PN18,19
  • Helps support venous tolerability through low osmolarity11,12,18–21

SmofKabiven Low Osmo Peripheral available in 3 sizes1

  • SmofKabiven Low Osmo Peripheral 6 gN, 1400 ml
  • SmofKabiven Low Osmo Peripheral 8 gN, 1950 ml
  • SmofKabiven Low Osmo Peripheral 10 gN, 2500 ml

ASPEN = American Society for Parenteral and Enteral Nutrition; ESPEN = European Society for Clinical Nutrition and Metabolism; gAA = grams amino acids; MCB: multi-chamber bag; N = nitrogen; PN = parenteral nutrition

*PN osmolarity: <850 mosmol/l according to ESPEN guidelines;11 <900 mosmol/l according to ASPEN guidelines;12
Compared with commercially available products: Triomel Peripheral (Baxter Healthcare)7, Lipoflex Peri (B Braun)8, Finomel Peri (Baxter Healthcare)9, Omeflex Peri (B Braun)10

Adverse events should be reported. Reporting forms and information can be found at https://yellowcard.mhra.gov.uk. Adverse events should also be reported to Fresenius Kabi Limited.
Email: Pharmacovigilance.GB@fresenius-kabi.com